Astressin is an amino-terminal truncated analog of CRF that retains high affinity binding to the extracellular domain of the receptor and is believed to act as a neutral competitive antagonist of receptor activation.

(1R,Z)-1-Hydroxy-1,4-dimethyl-6-(3-oxobutan-2-ylidene)-1,2,3,6,7,7a-hexahydro-5H-inden-5-one

Bobcat339 hydrochloride 是一种有效的、选择性的基于胞嘧啶的 TET 酶抑制剂，抑制 TET1 和 TET2 的 IC50 值分别为 33 μM 和 73 μM。Bobcat339 hydrochloride 可用于表观遗传学领域研究，并且可作为靶向 DNA 甲基化和基因转录新疗法的起点。